ABSTRACT
Background: The purpose of this study were to investigate the survival rate of patients with cervical cancer who were treated at our institution and to analyse its prognostic factors.Methods: One hundred twenty-two patients who underwent treatment for primary cervical cancer at Kochi Municipal Hospital between January 1996 and August 2003 (7 years 8 months) were retrospectively reviewed. There were 59 patients (48.4%) with stage 0 disease. Sixty-three patients (51.6%) had stage I-IV cervical cancer. The mean age was 56.7±15.6 years, and the median follow-up period was 31 months.Results: The overall 5-year suvival rate was 96.4% and 77.1% in stage I and II, respectively. The overall 3-year survival rate was 56.3% in stage III, and the 30-month survival rate was 0% in stage IV. Among the risk factors of histologic cell type, clinical parametrial involvement, clinical vaginal involvement and pelvic lymph node metastasis, clinical parametrial involvement had the lowest p value (p=0.0717) in a multivariate Cox proportional hazards regression analysis.;;Multivariate analysis using the Cox proportional hazard regression model showed that among the risk factors of histologic cell type, clinical parametrial involvement, clinical vaginal involvement and pelvic lymph mode metastasts, the lowest p value (p=0.0717) was for clinical parametrial involvement.Conclusion: Although there was no statistical significance comparing the prognostic factors in multivariate analysis, it was presumed that clinical parametrial involvement was the most influential factor among those which were analyzed in this study on the prognosis of patients with stage I-IV cervical cancer.
Subject(s)
Uterine Cervical NeoplasmsABSTRACT
A study was conducted to investigate muscle fatigue during isometric contraction of the indicis proprius using EMG analysis (BIMUTAS Ver. 2. 1) .<BR>The subjects were 8 healthy men (ranging in age from 19 to 42 years) .<BR>Plummets (ranging from 300g to 600g) were placed on the distal knuckle of the index finger to create loads on the indicis proprius muscle. EMG was recorded until the plummet dropped, and the total time required was divided into 10 equal parts. In each part, the EMG record for the first 1000 ms was picked out. Then the mean power frequency (MePF) and median power frequency (MdPF) of the power spectrum were calculated.<BR>The results were as follows:<BR>1) Both MePF and MdPF showed shits to lower frequency bands.<BR>2) Integrated values of the EMG power spectrum increased with time.<BR>3) The time courses of the MePF and MdPF in each EMG sample for the 8 subjects were determined by the 3-point moving average method.<BR>A break-point was observed in each MePF and MdPF diagram.<BR>It was considered that two-break points observed in the time courses of the EMG record were valid as an objective index of local muscle fatigue.